Table 3.
IgG Titres to the immunising antigen at specified time points
| Day | PfAMA1 | Tetanus toxoid | ||
|---|---|---|---|---|
| IgG (95 % CI) | N | IgG (95 % CI) | N | |
| Panel A. IgG titres to AMA1 FVO | ||||
| 0 | 5164 (2494–10,691) | 20 | 9938 (4484–22,025) | 20 |
| 28 | 13,888 (7017–27,484) | 20 | 10,475 (4892–22,428) | 20 |
| 56 | 14,954 (7923–28,222) | 20 | 9192 (4103–20,591) | 19 |
| 84 | 17,584 (9889–31,267) | 19 | 8744 (4184–18,276) | 18 |
| 140 | 14,048 (7808–25,275) | 20 | 12,793 (7187–22,773) | 20 |
| 364 | 6925 (3295–14,555) | 19 | 6551 (2896–14,818) | 16 |
| Panel B. Titre changes following vaccination (fold increase) | ||||
| 0 | 1 | 20 | 1 | 20 |
| 28 | 2.69 (1.73–4.18) | 20 | 1.05 (0.87–1.28) | 20 |
| 56 | 2.90 (1.87–4.48) | 20 | 0.93 (0.70–1.25) | 19 |
| 84 | 3.53 (2.30–5.42) | 19 | 1.07 (0.72–1.58) | 18 |
| 140 | 2.72 (1.88–3.94) | 20 | 1.29 (0.86–1.93) | 20 |
| 364 | 1.46 (1.02–2.09) | 19 | 0.89 (0.61–1.28) | 16 |