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Simulation results for the design in Fig. 2: the estimated means, based on 500 replicates, are reported for the final outcomes of the four adaptive interventions embedded in the design with interactions in model (4)
| Mean of the final outcomes | |||||
| (−1,1) | (−1,-1) | (1,1) | (1,-1) | ||
| Simulated means | 5.487 | 4.622 | 6.032 | 6.059 | |
| Estimated means by joint model | 5.502 | 4.610 | 6.047 | 6.046 | |
| Estimated means by TVMEM | 5.500 | 4.611 | 6.045 | 6.048 | |
