Table 9.

Simulation results from the alternative simulation approach: the estimated means, based on 500 replicates, are reported for coefficients in model (4)

Parameter estimation
		β 12	β 23	β 32	β 42
		(first-stage intervention A 1)	(second-stage interventions for responder A 2NR)	(time of intervention T 2)	(interaction term A 1 . A 2NR)
True value		−0.6	0.5	0.4	−1.5
Joint model	Estimate	−0.608	0.492	0.447	−1.338
	MSE	0.002	0.003	0.018	0.034
	CI%	97 %	96 %	87 %	70 %
	Length of CI	0.199	0.192	0.376	0.411
TVMEM	Estimate	−0.534	0.492	0.448	−2.367
	MSE	0.007	0.003	0.020	0.763
	CI%	74 %	93 %	84 %	0 %
	Length of CI	0.197	0.191	0.376	0.529

CI%: Coverage probability of the 95 % confidence interval

MSE mean squared error