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. 2016 Aug 30;35(1):129. doi: 10.1186/s13046-016-0407-y

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — ATO induces MET and attenuates the invasive capacities of chondrosarcoma cells through miR-125b. HCS-2/8 cells were transfected with a con-mimic or miR-125b-mimic for 12 h. a qRT-PCR analyses of miR-125b and CDH-1 levels (mean ± SD, n = 3). b Western blot analyses and (c) relative protein levels of E-cadherin, N-cadherin, Slug and MMP9 (mean ± SD, n = 3). **P < 0.01 and *P < 0.05 compared with control cells or cells transfected with con-mimic. After HCS-2/8 cells were transfected by anti-con or anti-miR-125b for 12 h, they were exposed to 1.5 μM ATO for 48 h. d qRT-PCR analyses of miR-125b and CDH-1 levels (mean ± SD, n = 3); e Western blot analyses and (f) relative protein levels of E-cadherin and N-cadherin (mean ± SD, n = 3)