Table 4.
C1065A. Genotype and clinical characteristics of T2DM patients and healthy control
| Healthy control | T2DM | P-value | ||||
|---|---|---|---|---|---|---|
| CC | CA + AA | CC | CA + AA | CC vs. (CA + AA) in healthy control | CC vs. (CA + AA) in T2DM patients | |
| N (male/femal) | 18/18 | 22/18 | 66/49 | 83/61 | 0.663 | 0.968 |
| AGE (yrs) | 55.00 ± 8.24 | 57.35 ± 8.84 | 57.50 ± 10.41 | 55.39 ± 12.23 | 0.236 | 0.141 |
| SBP (mmHg) | 118.31 ± 13.08 | 116.50 ± 12.62 | 139.84 ± 22.64 | 136.01 ± 19.29 | 0.542 | 0.142 |
| DBP (mmHg) | 76.39 ± 8.38 | 75.65 ± 7.32 | 85.13 ± 11.59 | 82.09 ± 11.10 | 0.683 | 0.033 |
| DM duration (yrs) | 6.32 ± 5.62 | 6.71 ± 6.00 | 0.600 | |||
| HbA1c (%) | 9.80 ± 2.51 | 9.37 ± 2.45 | 0.171 | |||
| Cr (umol/L) | 66.38 ± 16.05 | 63.39 ± 13.22 | 72.97 ± 30.90 | 76.68 ± 32.38 | 0.376 | 0.351 |
| CYS-C (mg/L) | 0.97 ± 0.20 | 0.97 ± 0.22 | 1.19 ± 0.53 | 1.16 ± 0.46 | 0.892 | 0.581 |
| SOD (U/mL) | 107.25 ± 10.84 | 106.20 ± 10.67 | 81.30 ± 19.61 | 82.58 ± 29.86 | 0.672 | 0.692 |
| FPG (mmol/L) | 5.28 ± 0.38 | 5.42 ± 0.33 | 9.92 ± 3.55 | 9.07 ± 3.10 | 0.087 | 0.041 |
| TC (mmol/L) | 4.18 ± 0.51 | 4.33 ± 0.53 | 4.49 ± 1.44 | 4.44 ± 1.02 | 0.206 | 0.767 |
| TG (mmol/L) | 1.16 ± 0.42 | 1.20 ± 0.42 | 2.19 ± 1.63 | 2.20 ± 2.08 | 0.647 | 0.957 |
| HDL-C (mmol/L) | 1.42 ± 0.20 | 1.41 ± 0.20 | 1.20 ± 0.31 | 1.22 ± 0.32 | 0.875 | 0.552 |
| LDL-C (mmol/L) | 2.24 ± 0.40 | 2.38 ± 0.41 | 2.53 ± 0.82 | 2.52 ± 0.78 | 0.142 | 0.936 |
| ApoA-I (g/L) | 1.64 ± 0.25 | 1.68 ± 0.28 | 1.27 ± 0.36 | 1.32 ± 0.31 | 0.500 | 0.240 |
| ApoB (g/L) | 0.72 ± 0.17 | 0.77 ± 0.19 | 0.89 ± 0.32 | 0.91 ± 0.35 | 0.232 | 0.597 |
| LP (a) (mg/L) | 117.72 ± 86.94 | 143.92 ± 132.57 | 156.66 ± 231.64 | 157.40 ± 152.60 | 0.317 | 0.975 |
| apoM (ng/uL) | 24.34 ± 11.02 | 24.62 ± 11.96 | 19.21 ± 8.46 | 20.93 ± 11.10 | 0.917 | 0.171 |
Data are means ± SD. P-Value <0.05 was shown in bold