Table 5.
T855C. Genotype and clinical characteristics of T2DM patients and healthy control
| Healthy control | T2DM | P-value | ||||
|---|---|---|---|---|---|---|
| TT | TC + CC | TT | TC + CC | TT vs. (TC + CC) in healthy control | TT vs. (TC + CC) in T2DM patients | |
| N (male/femal) | 21/26 | 19/10 | 90/72 | 59/38 | 0.077 | 0.406 |
| AGE (yrs) | 56.83 ± 9.37 | 55.28 ± 7.19 | 56.12 ± 12.14 | 56.68 ± 10.35 | 0.447 | 0.703 |
| SBP (mmHg) | 116.28 ± 13.45 | 119.10 ± 11.64 | 138.06 ± 20.66 | 137.13 ± 21.37 | 0.353 | 0.732 |
| DBP (mmHg) | 75.02 ± 7.37 | 77.59 ± 8.31 | 83.54 ± 11.54 | 83.27 ± 11.22 | 0.165 | 0.851 |
| DM duration (yrs) | 6.41 ± 5.84 | 6.74 ± 5.84 | 0.657 | |||
| HbA1c (%) | 9.61 ± 2.51 | 9.48 ± 2.44 | 0.663 | |||
| Cr (umol/L) | 62.20 ± 13.06 | 69.02 ± 16.17 | 74.91 ± 33.70 | 75.23 ± 28.29 | 0.047 | 0.938 |
| CYS-C (mg/L) | 0.95 ± 0.21 | 0.99 ± 0.21 | 1.18 ± 0.50 | 1.16 ± 0.48 | 0.418 | 0.789 |
| SOD (U/mL) | 106.64 ± 11.45 | 106.79 ± 9.53 | 83.19 ± 29.26 | 80.03 ± 18.55 | 0.952 | 0.341 |
| FPG (mmol/L) | 5.35 ± 0.36 | 5.36 ± 0.36 | 9.42 ± 3.29 | 9.50 ± 3.41 | 0.931 | 0.858 |
| TC (mmol/L) | 4.35 ± 0.48 | 4.12 ± 0.57 | 4.55 ± 1.36 | 4.32 ± .94 | 0.075 | 0.149 |
| TG (mmol/L) | 1.18 ± 0.39 | 1.18 ± 0.47 | 2.27 ± 2.03 | 2.07 ± 1.63 | 0.956 | 0.409 |
| HDL-C (mmol/L) | 1.42 ± 0.19 | 1.41 ± 0.22 | 1.21 ± 0.32 | 1.22 ± 0.31 | 0.940 | 0.810 |
| LDL-C (mmol/L) | 2.40 ± 0.37 | 2.18 ± 0.43 | 2.56 ± 0.83 | 2.47 ± 0.74 | 0.023 | 0.370 |
| ApoA-I (g/L) | 1.67 ± 0.26 | 1.64 ± 0.28 | 1.30 ± 0.34 | 1.28 ± 0.34 | 0.640 | 0.713 |
| ApoB (g/L) | 0.76 ± 0.18 | 0.72 ± 0.19 | 0.94 ± 0.37 | 0.85 ± 0.27 | 0.334 | 0.034 |
| LP (a) (mg/L) | 154.47 ± 128.70 | 94.30 ± 69.74 | 161.87 ± 219.55 | 149.06 ± 132.16 | 0.023 | 0.603 |
| apoM (ng/uL) | 26.63 ± 11.92 | 21.02 ± 9.87 | 20.55 ± 10.55 | 19.53 ± 9.13 | 0.037 | 0.427 |
Data are means ± SD. P-Value <0.05 was shown in bold