Table 6.
T778C. Genotype and clinical characteristics of T2DM patients and healthy control
| Healthy control | T2DM | P-value | ||||
|---|---|---|---|---|---|---|
| TT | TC + CC | TT | TC + CC | TT vs. (TC + CC) in healthy control | TT vs. (TC + CC) in T2DM patients | |
| N (male/femal) | 29/27 | 11/9 | 131/97 | 18/13 | 0.805 | 0.949 |
| AGE (yrs) | 55.21 ± 8.76 | 59.10 ± 7.57 | 56.12 ± 11.71 | 56.81 ± 13.34 | 0.082 | 0.764 |
| SBP (mmHg) | 118.73 ± 12.32 | 113.50 ± 13.58 | 136.83 ± 20.59 | 136.06 ± 24.20 | 0.117 | 0.851 |
| DBP (mmHg) | 76.57 ± 8.23 | 74.40 ± 6.34 | 83.11 ± 11.20 | 81.97 ± 11.44 | 0.288 | 0.598 |
| DM duration (yrs) | 6.49 ± 5.81 | 6.41 ± 5.61 | 0.943 | |||
| HbA1c (%) | 9.51 ± 2.48 | 9.58 ± 2.37 | 0.875 | |||
| Cr (umol/L) | 64.42 ± 13.46 | 65.88 ± 17.78 | 76.19 ± 33.37 | 74.30 ± 24.27 | 0.705 | 0.761 |
| CYS-C (mg/L) | 0.96 ± 0.19 | 0.98 ± 0.27 | 1.19 ± 0.53 | 1.15 ± .38 | 0.738 | 0.730 |
| SOD (U/mL) | 106.93 ± 10.18 | 106.05 ± 12.28 | 80.89 ± 20.97 | 77.42 ± 24.34 | 0.755 | 0.401 |
| FPG (mmol/L) | 5.38 ± 0.37 | 5.28 ± 0.32 | 9.43 ± 3.38 | 9.59 ± 3.22 | 0.249 | 0.813 |
| TC (mmol/L) | 4.24 ± 0.55 | 4.33 ± 0.45 | 4.36 ± 0.95 | 4.05 ± .93 | 0.525 | 0.097 |
| TG (mmol/L) | 1.16 ± 0.41 | 1.25 ± 0.45 | 2.14 ± 1.60 | 1.98 ± 1.35 | 0.401 | 0.596 |
| HDL-C (mmol/L) | 1.42 ± 0.20 | 1.40 ± 0.18 | 1.20 ± 0.31 | 1.19 ± 0.37 | 0.806 | 0.840 |
| LDL-C (mmol/L) | 2.30 ± 0.41 | 2.35 ± 0.41 | 2.49 ± 0.76 | 2.32 ± 0.74 | 0.596 | 0.224 |
| ApoA-I (g/L) | 1.65 ± 0.24 | 1.69 ± 0.34 | 1.28 ± 0.32 | 1.22 ± 0.32 | 0.625 | 0.350 |
| ApoB (g/L) | 0.75 ± 0.18 | 0.75 ± 0.18 | 0.89 ± 0.31 | 0.83 ± 0.29 | 0.950 | 0.318 |
| LP (a) (mg/L) | 121.14 ± 97.43 | 160.56 ± 148.32 | 160.62 ± 203.15 | 156.10 ± 119.13 | 0.183 | 0.904 |
| apoM (ng/uL) | 23.35 ± 10.91 | 27.68 ± 12.58 | 20.05 ± 10.21 | 18.20 ± 8.53 | 0.148 | 0.337 |