Table 2.
Studies’ characteristics
Study | Year | Country | Study design | Inclusion criteria | Exclusion criteria | Primary outcome | Sample size | Elegible patients | Analysis | Enrolled patients | Laparoscopic drainage | Bowel resection | Study quality | Limits |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DILALA | 2010–2014 | Sweden, Denmark | multicentric RCT | patients with Hinchey III diverticulitis at diagnostic laparoscopy | not reported | reoperation at 12 months | 64 | not reported | ITT | 83 | 43 | 40 | High | |
SCANDIV | 2010–2014 | Sweden, Norway | multicentric RCT | patients with free air at abdominal CT scan | obstruction pregnancy | severe complications and death at 90 days | 130 | 216 | modified ITT | 144a | 74a | 70a | High | includes also patients with Hinchey I-II |
LADIES | 2010–2013 | Belgium, Netherlands, Italy | multicentric RCT | patients with Hinchey III diverticulitis at diagnostic laparoscopy | dementia, previous abdominal irradiation, high dose steroidal therapy, shock, age >85 | severe complications and mortality at 12 months | 264 | 241 | ITT | 88 | 46 | 42 | High | premature ending |
a subgroup analysis of patients with Hinchey grade I-II-III diverticulitis