. 2016 Aug 30;17(1):328. doi: 10.1186/s12859-016-1198-z

Table 4.

Average percentage of the number of topologies showing improvements for the combined topology-based matrices compared with the three generic matrices (Blosum62, VT160_RA, and VTML200)

	% showing improvements
	Blosum62 combined	VT160_RA combined
All helical	73	73
All beta sheet	53	49
Mixed alpha and beta^a	56	56

The percentage improvements are shown for the Blosum62 combined topology-based matrices and the VT160_RA combined topology-based matrices. The results are shown for all helical, all beta sheet and mixed alpha and beta classes. Both types of combined topology-based matrices perform nearly equally well. The topology-based combined matrices show their best performances for all helical class

^aMixed alpha and beta corresponds to the combined group of alpha + beta structures and alpha/beta structures (consistent with CATH)