Table 2.
Treatment | Plasma levels |
|
---|---|---|
SR10171 (μM) | Rosi (μM) | |
C57BL6 on RD 4 days treatment: SR10171 – 5 mg/kg/d; Rosi – 5 mg/kg/d |
4.01 | 1.67 |
DIO model on HFD 4 wks treatment: SR10171 – 22.1 mg/kg/d; Rosi – 24.2 mg/kg/d |
14.25 | 0.10 |
C57BL/6 on RD 8 wks treatment: SR10171 – 12.7 mg/kg/d; Rosi – 11.7 mg/kg/d |
15.97 | 6.28 |