Table 3.
Proportion of participants exhibiting changes in PSP scores in each dimension at each visit
| PSP | FASa (n=90)
|
|||
|---|---|---|---|---|
| Baseline | Week 4 | Week 12 | Week 24 | |
| Socially useful activities, including work and study, n (%) | ||||
| Absent | 3 (3.33) | 3 (3.33) | 4 (4.44) | 7 (7.78) |
| Mild | 10 (11.11) | 15 (16.67) | 25 (27.78) | 43 (47.78) |
| Manifest | 28 (31.11) | 50 (55.56) | 49 (54.45) | 33 (36.66) |
| Marked | 34 (37.78) | 20 (22.22) | 11 (12.22) | 6 (6.67) |
| Severe | 15 (16.67) | 2 (2.22) | 1 (1.11) | 1 (1.11) |
| Very severe | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
| P-valueb | <0.0001 | <0.0001 | <0.0001 | |
| Personal and social relationships, n (%) | ||||
| Absent | 1 (1.11) | 2 (2.22) | 4 (4.44) | 10 (11.11) |
| Mild | 10 (11.11) | 21 (23.33) | 33 (36.67) | 47 (52.22) |
| Manifest | 35 (38.90) | 49 (54.45) | 46 (51.11) | 26 (28.90) |
| Marked | 31 (34.44) | 13 (14.44) | 5 (5.56) | 4 (4.44) |
| Severe | 13 (14.44) | 5 (5.56) | 2 (2.22) | 3 (3.33) |
| Very severe | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
| P-valueb | <0.0001 | <0.0001 | <0.0001 | |
| Self-care, n (%) | ||||
| Absent | 22 (24.44) | 34 (37.78) | 43 (47.78) | 54 (60.00) |
| Mild | 30 (33.33) | 39 (43.33) | 36 (40.00) | 27 (30.00) |
| Manifest | 24 (26.67) | 14 (15.56) | 9 (10.00) | 7 (7.78) |
| Marked | 14 (15.56) | 3 (3.33) | 2 (2.22) | 2 (2.22) |
| Severe | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
| Very severe | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
| P-valueb | <0.0001 | <0.0001 | <0.0001 | |
| Disturbing and aggressive behaviors, n (%) | ||||
| Absent | 45 (50.00) | 58 (64.44) | 69 (76.67) | 71 (78.89) |
| Mild | 27 (30.00) | 24 (26.67) | 12 (13.33) | 10 (11.11) |
| Manifest | 8 (8.88) | 7 (7.78) | 8 (8.89) | 8 (8.89) |
| Marked | 5 (5.56) | 1 (1.11) | 1 (1.11) | 1 (1.11) |
| Severe | 5 (5.56) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
| Very severe | 0 (0.00) | 0 (0.00) | 0 (0.00) | 0 (0.00) |
| P-valueb | – | – | – | |
Notes:
a
Missing data were filled by LOCF method for each visit.
b
Bowker tests were used to analyze the change after treatment and calculate P-value.
Abbreviations: FAS, full analysis set; LOCF, last observation carried forward; PSP, personal and social performance.