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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Behav Brain Res. 2016 Aug 1;314:96–105. doi: 10.1016/j.bbr.2016.07.052

Figure 5. Running increases levels of adult neurogenesis.

Figure 5

Total number of bromodeoxyuridine (BrdU) positive cells is used as an estimate of hippocampal neurogenesis. Running significantly increased the number of BrdU+ cells in alcohol-exposed and saline-exposed mice in both Experiment 1 (A) and Experiment 2 (B) as well as the number of DCX+ cells in Experiment 2 (C) Representative image of a BrdU/DAB stained coronal section from a saline-sedentary (D) and saline-runner (E). Representative image of a DCX/DAB stained coronal section of a saline-sedentary (F) and saline-runner (G). Note: differences between experiments in the number of BrdU+ cells are expected due to variation in the BrdU immunohistochemical signal to noise between batches. All values represent mean ± SEM. #p < 0.001, *p < 0.05.