Table 2.
Trial with alternate allocation to BCG or no BCG at birth, at 1 year and at 3 years of age. Alger, 1935–1952 (Sergent et al., 1954).
| Age | Mortality risk (deaths/person-years)a | Mortality rate ratio (BCG/no BCG) |
|
|---|---|---|---|
| Randomised to BCG-vaccination | Randomised to no BCG vaccination | ||
| 1st year of life (before and after enrolment) | 20.4% (4121/20167) | 21.0% (4008/19092) | 0.97 (0.93–1.02) |
| 2nd-3rd year (after first revaccination of BCG group) | 5.9% (1721/29310) | 7.1% (1919/27233) | 0.83 (0.78–0.89) |
| 4th–5th year (after second revaccination of BCG group) | 1.0% (243/25444) | 1.8% (414/23034) | 0.53 (0.45–0.62) |
a
The paper indicated the number of children under observation at the beginning of each year. It has been assumed that all were followed for 365 days.