Table 1.
Demographics and clinical characteristics of patients in the CIK treatment and surgery alone groups.
| Clinicopathological variables | Surgery alone group (n = 217) | CIK treatment group (n = 231) | p value |
|---|---|---|---|
| Age (y) | 0.292 | ||
| <50 | 118 | 137 | |
| ≥50 | 99 | 94 | |
| Median (range) | 48 (22–74) | 47 (14–80) | |
| Gender | 0.068 | ||
| Male | 198 | 198 | |
| Female | 19 | 33 | |
| Capsule | 0.880 | ||
| Complete | 183 | 196 | |
| Incomplete | 34 | 35 | |
| Tumor size (cm) | 0.781 | ||
| ≤5 | 93 | 96 | |
| >5 | 124 | 135 | |
| TNM stage | 0.539 | ||
| I | 122 | 136 | |
| II | 31 | 25 | |
| III | 64 | 70 | |
| Tumor number | 0.142 | ||
| Single | 181 | 180 | |
| Multiple | 36 | 51 | |
| Histological differentiation | 0.653 | ||
| Well | 34 | 43 | |
| Moderate | 133 | 133 | |
| Poor | 50 | 55 | |
| Virus infection | 0.090 | ||
| HBV | 195 | 198 | |
| HCV | 1 | 1 | |
| HBV+HCV | 3 | 1 | |
| Non | 18 | 31 | |
| Child-Pugh classes | 0.414 | ||
| A | 205 | 222 | |
| B | 12 | 9 | |
| Alcoholic liver disease | 0.924 | ||
| Yes | 9 | 10 | |
| No | 208 | 221 | |
| NASH | 0.700 | ||
| Yes | 8 | 7 | |
| No | 209 | 224 | |
| AFP (ng/mL) | 0.433 | ||
| Median | 173.3 | 254.5 | |
| Range | 0.64–1,21,000 | 0-1,21,000 | |
| PD-L1 | 0.960 | ||
| <1% | 111 | 116 | |
| 1–5% | 54 | 57 | |
| ≥5% | 52 | 58 |
HBsAg, Hepatitis B surface antigen; AFP, α-fetoprotein; NASH, non-alcoholic steatohepatitis.