Table 3.

Univariate and multivariate analyses for DFS.

	Univariate			Multivariate
Variables	HR	95% CI	p value	HR	95% CI	p value
Age	0.671	0.406–1.111	0.121
Gender	0.980	0.355–2.707	0.969
TNM Stage	2.725	1.534–4.801	0.001	2.994	2.950–5.464	0.001
Grade	1.410	0.839–2.369	0.195
HBV	2.532	0.914–6.993	0.074	2.288	0.816–6.410	0.116
Tumor size	1.151	0.702–1.883	0.579
Tumor number	1.898	0.857–4.202	0.114
Vascular invasion	3.931	1.202–12.855	0.024	2.418	0.821–7.121	0.109
CD8	0.593	0.360–0.976	0.040	0.559	0.321–0.971	0.039
PD-L1	0.433	0.206–0.912	0.028	0.655	0.299–1.436	0.291

Abbreviations: HR, Hazard ratio; CI, Confidence Interval of the estimated HR.