Table 4.

Univariate and multivariate analyses for OS.

	Univariate			Multivariate
Variables	HR	95% CI	p value	HR	95% CI	p value
Age	0.564	0.287–1.108	0.096	1.802	0.901–3.571	0.092
Gender	0.671	0.161–2.790	0.583
TNM Stage	2.950	1.443–2.950	0.003	3.509	1.629–7.576	0.001
Grade	1.279	0.650–2.513	0.476
HBV	2.353	0.565–9.804	0.239
Tumor size	1.041	0.542–1.996	0.906
Tumor number	1.876	0.729–4.831	0.191
Vascular invasion	5.096	1.770–14.668	0.003	2.478	0.824–7.453	0.106
CD8+	0.307	0.148–0.636	0.001	0.329	0.148–0.731	0.006
PD-L1	0.339	0.104–1.106	0.073	0.527	0.153–1.818	0.311

Abbreviations: HR, Hazard ratio; CI, Confidence Interval of the estimated HR.