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Myeloid PTEN-deficiency increases tumor growth of B16-F10 melanoma. (A) Representative bioluminescence images of myPTEN+/+ and myPTEN−/− mice on day 2, day 6 and day10 after s.c. B16-F10-Ova-Luc injection, (B) Quantification of tumor growth by bioluminescence imaging of luciferase activity, n = 10–14. (C) Weight change of B16-injected mice, values are expressed as percent initial weight before tumor inoculation, n = 4 – 7.
