TABLE 1.

Clinicopathologic and Genetic Summary of SMARCB1-Deleted Tumors with EWSR1 FISH Alterations

Case	Age (yrs)/Sex	Location	Initial diagnosis	Final diagnosis	SMARCB1 deletion	EWSR1 break apart FISH result	Other pertinent results
1	3/F	Clivus	Myoepithelial carcinoma	Poorly differentiated chordoma	Homozygous	Break-apart with deletion	T-brachyury IHC positive
2	5/M	Abdominal wall	Ewing sarcoma	Malignant rhabdoid tumor	Homozygous	Break-apart with deletion	FLI1, ERG FISH negative
3	16/F	Dura mater	Myoepithelial carcinoma	Myoepithelial carcinoma	Homozygous	Heterozygous deletion and break-apart	POU5F1, PBX1/3, KLF17 FISH negative
4	21/M	Groin	Extraskeletal myxoid chondrosarcoma	Epithelioid sarcoma	Heterozygous	Heterozygous deletion	NR4A5 FISH negative

FISH, fluorescence in situ hybridization; IHC, immunohistochemistry..