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. 2016 Aug 31;10(8):e0004900. doi: 10.1371/journal.pntd.0004900

Fig 4. Cytokine gene expression in C57BL/6 mouse footpads infected with Leishmania (L.) amazonensis and treated with Morinda citrifolia fruit juice.

Fig 4

Relative quantification of IFN-γ (A), iNOS (B), IL-12 (C), TNF-α (D), IL-10 (E), TGF-β (F) and IL-4 (G) with RPLP0 as endogenous control. Noni group treated at 500mg.kg-1.day-1 and Glucantime group treated at 20mg.kg-1.twice a week-1, both during 60 days. Data represent mean ± SD of two experiments realized in triplicate. *p<0.05, **p<0.01, ***p<0.001 when compared with control group or between group brackets by two-way ANOVA and Bonferroni’s post-test. RQ: relative quantification; RPLP0: ribosomal protein large P0; La+Noni: group infected and treated with Noni; La+Glucantime: group infected and treated with Glucantime; La: group infected and mock-treated; Noni: group mock-infected and treated with Noni; Normal: mock-infected and mock-treated group.