Table 3. Incidence and risk difference (RD) of self-reported fever episodes among household members that attended the mass drug administration (MDA) of artesunate/amodiaquine malaria chemoprevention (ASAQ-CP) in rounds 1 and 2 during the Ebola outbreak, Monrovia, Liberia, 2014.
Responses for all household members | Incidence of self-reported fever episodes (%) in the month prior to round 1 | Incidence of self-reported fever episodes (%) in the month prior to round 2 | RD (%) of self-reported fever episodes | (95% CI for RD) | p-value | |
---|---|---|---|---|---|---|
All household members (N = 1229ᶲ) | 4.2 | 1.5 | 2.7 | (1.4; 4.0) | <0.001* | |
Incidence of self-reported fever by ASAQ-CP adherence | ||||||
Household members who completed ASAQ-CP in round 1 (N = 592‡) | 6.4 | 1.5 | 4.9 | (2.7; 7.1) | <0.001* | |
Household members who did not start or complete ASAQ-CP in round 1 (N = 511‡) | 2.2 | 1.6 | 0.6 | (-1.1; 2.2) | 0.690 | |
Incidence of self-reported fever by age group | ||||||
Household members >5 years old (N = 1044) | 3.8 | 1.6 | 2.2 | (0.8; 3.6) | 0.002* | |
Household members < = 5 years old (N = 185) | 6.5 | 1.1 | 5.4 | (1.6; 9.2) | 0.006* |
ᶲ 6 household members for whom incidence of self-reported fever is unknown were excluded
‡ Further 126 household members for whom compliance with ASAQ-CP initiation or adherence was unknown were excluded from analysis
* Significant difference in incidence of self-reported fever between round 1 and 2 of the MDA