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. 2016 Aug 31;11(8):e0156701. doi: 10.1371/journal.pone.0156701

Fig 5. Inhibition of BRD7 promoted ERK phosphorylation in lung adenocarcinoma.

Fig 5

(A) The protein expression level of BRD7 was measured by using Western blot. (B) The mRNA expression level of BRD7 was measured by using qRT-PCR. (C) Inhibition of BRD7 promoted the ERK phosphorylation in the A549 cells. (D) CCK8 analysis was used to measure the A549 cell proliferation. (E) Overexpression of BRD7 suppressed the ERK phosphorylation in the A549 cells. (F) Wound-healing assay was performed to measure the A549 cell migration. (G) Relative ratio of wound closure per field is shown. *p<0.05 and ***p<0.001.