BD regulates circulating enterohormones. Sera were collected at 8 wk postsurgery and subjected to enterohormone analysis by the Bio-Plex Pro Mouse Diabetes 8-Plex Assay kit (Bio-Rad). A: circulating GLP-1; *BD vs. all other groups, P < 0.05. B: circulating insulin; *DIO vs. all other groups, P < 0.05. C: circulating leptin; *DIO vs. all other groups, P< 0.05. D: circulating resistin; *DIO vs. all other groups, P < 0.05. E: circulating ghrelin; *WMS vs. DIO, P < 0.05. F: relationship between total bile acids and circulating GLP-1 levels in DIO and BD mice (P < 0.001). G: relationship between total bile acids and circulating insulin levels in DIO and BD mice (P = 0.13); H: relationship between total bile acids and leptin levels in DIO and BD mice (P = 0.05); I: relationship between total bile acids and resistin levels in DIO and BD mice (n = 5, P = 0.05); J: relationship between total bile acids and ghrelin levels in DIO and BD mice (P = 0.54); n = 9 in each group. All values are presented as means ± SE.