Figure 2.

Effects of valencene on DNCB-induced atopy-like dermatitis in NC/Nga mice. (a) Representative clinical features and (b) corresponding histological analyses (hematoxylin and eosin or toluidine blue staining) and immunohistochemical staining of filaggrin of mouse back skin were shown, respectively (magnification: ×400). (c) SCORAD index, scratching score, and dorsal skin thickness were assessed using the criteria described in Section 2. (d) Body weight and spleen weight were measured. Data were expressed as means ± SDs (n = 4 per experiment). ^∗ p < 0.05 versus DNCB alone. Bar = 250 μm.