Table 3.
Depression status, recovery, and response at 12 months
| CBT | BA |
Observed data only |
Observed and imputed data |
|||
|---|---|---|---|---|---|---|
| Odds ratio | p value | Odds ratio | p value | |||
| SCID depression | ||||||
| Baseline | 219/219 (100%) | 221/221 (100%) | ||||
| mITT | 37/163 (23%) | 31/154 (20%) | 0·9 (0·5–1·6) | 0·71 | 0·9 (0·5–1·6) | 0·70 |
| PP | 30/141 (21%) | 24/128 (19%) | 0·9 (0·5–1·7) | 0·80 | 0·9 (0·5–1·7) | 0·75 |
| Depression recovery* | ||||||
| mITT | 124/189 (66%) | 115/175 (66%) | 1·0 (0·6–1·5) | 0·96 | 1·2 (0·7–1·9) | 0·53 |
| PP | 104/151 (69%) | 94/135 (70%) | 1·0 (0·6–1·7) | 0·96 | 1·2 (0·7–2·0) | 0·47 |
| Depression response† | ||||||
| mITT | 117/189 (62%) | 107/175 (61%) | 1·0 (0·9–1·1) | 0·73 | 0·9 (0·6–1·4) | 0·75 |
| PP | 100/151 (66%) | 87/135 (64%) | 0·9 (0·9–1·0) | 0·64 | 0·9 (0·5–1·4) | 0·55 |
Data are n/N (%) or odds ratio (95% CI). CBT=cognitive behavioural therapy. BA=behavioural activation. SCID=Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. mITT=modified intention to treat. PP=per protocol.
*
Participants with Patient Health Questionnaire 9 scores of 9 or less.
†
Participants with a 50% reduction from baseline in Patient Health Questionnaire 9 score.