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. 2016 Aug 26;7:12508. doi: 10.1038/ncomms12508

Figure 5. CYLD regulates CEP-1/p53-dependent cell death upon DNA damage in C. elegans.

Figure 5

(a) Representative pictures showing the pachytene region of the germline and quantification of corpses formation 24 h after 90 Gray (Gy) irradiation from cep-1 and cyld-1 RNAi fed worms (arrows indicate apoptotic corpses). Data shown as mean±s.d is shown. Statistical significance was determined with Student's t-test; ***P≤0.0005. Scale bars, 20 μm. (b) Quantification of germ cell corpses in the indicated worm lines after irradiation. One representative out of three independent experiments is shown. Data shown as mean. Statistical significance was determined with Student's t-test; *P≤0.05, **P≤0.005. (c) Quantification of germ cell corpses in the indicated worms 24 h after irradiation. Data shown as mean±s.d. is shown. Statistical significance was determined with Student's t-test; *P≤0.05, **P≤0.005, ***P≤0.0005. One representative out of three independent experiments is shown.