Table 3.
The level of phospholipid fatty acids [ph-LA, ph-AA, and ph-DHA], lipid peroxidation products [4-HNE, MDA, 4-ONE], and 4-HNE – protein adducts in the lung cancer tissue [SCC, n=38 and AC, n=34] and lung tissue.
| Analysed parameter | SCC n=38 |
AC n=34 |
||
|---|---|---|---|---|
| Lung tissue | Cancer tissue | Lung tissue | Cancer tissue | |
| ph-LA [µg/ml] | 20.95± 2.27 | 11.98±1.70a | 18.92±2.55 | 11.36±5.97a |
| ph-AA [µg/ml] | 46.17±3.51 | 27.30±4.98a | 44.10±5.01 | 33.81±4.29a |
| ph-DHA [µg/ml] | 11.72±1.70 | 7.06±1.02a | 10.04±1.13 | 4.99±0.97a,b |
| 4-HNE [nmoles/ml] | 3.46±1.31 | 9.63±2.60a | 3.42±1.65 | 8.08±2.87a |
| MDA [nmoles/ml] | 17.24±2.53 | 70.10±9.73a | 19.71±3.24 | 115.52±13.65a,b |
| 4-ONE [nmoles/ml] | 0.23±0.04 | 0.52±0.30 | 0.30±0.08 | 0.59±0.56 |
| 4-HNE – protein adducts [pmoles/mg protein] | 50.07±9.81 | 73.02±8.31a | 59.87±3.65 | 103.49±8.79a,b |
a
Statistically significant differences vs. control group, p<0.05.
b
Statistically significant differences vs. SCC group, p<0.05.