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. 2016 Sep 1;6:32323. doi: 10.1038/srep32323

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Copyright © 2016, The Author(s)

This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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Intracellular total protein synthesis (A) and ALP activity (B) of osteoblasts osteo-induced by different alloy extracts 14 days of incubation. Cells cultured in osteogenic medium (α-MEM medium with 10% FBS, 0.01 μM dexamethasone, 50 ug/mL ascorbic acid and 10 mM Na-β-glycerophosphate) were set as the blank control. The ALP activity of four Mg alloys group were elevated and significantly higher than the blank control (p < 0.05), and Mg-1Ca-2.0Sr reached the highest value. All data represent the mean ± standard deviation of three independent experiments. ^#p < 0.05 and ^##p < 0.01 compared with the blank control group.