Figure 12. Role of the JNK signaling pathway in podocyte protection.
(A) Western blot analysis of Phospho-JNK and JNK before and after SP600125 (JNK inhibitor) incubation in PAN treated podocytes (6 h after incubation). (B) Flow cytometric analysis of podocyte apoptosis with or without SP600125 after PAN treatment (*P < 0.05). The experiments were performed for 3 times, and the results were shown as mean ± SD. (C) Immunofluorescence of F-actin in PAN treated mouse podocytes after SP600125 incubation. Original magnification, X400.