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. 2016 Sep 1;6:32076. doi: 10.1038/srep32076

Table 3. Geometric mean antibody titres (ug/ml) for pneumococcal OPA.

Serotype W0 GMT (95% CI) pa Week 8 GMT (95% CI) pa Week 28 GMT (95% CI) pa
PCV13 + PPSV23 n = 27 PPSV23 n = 33 PCV13 + PPSV23 n = 26 PPSV23 n = 28 PCV13 + PPSV23 n = 26 PPSV23 n = 27
1 4.98 (4.07–6.08) 4.80 (4.02–5.73) 0.89 27.35 (13.97–53.54) 33.42 (18.11–61.66) 0.85 12.20 (7.31–20.37) 12.34 (8.51–17.91) 0.29
3 5.28 (3.63–7.69) 5.28 (3.80–7.32) 0.91 19.53 (11.78–32.37) 13.36 (7.46–23.93) 0.66 6.91 (4.50–10.61) 5.95 (4.33–8.18) 0.36
4 10.19 (4.48–23.17) 6.77 (3.66–12.53) 0.67 938 (397–2216) 431 (153–1218) 0.26 281 (95.08–828) 50.05 (15.96–157) 0.26
5 5.39 (4.10–7.09) 4.42 (3.79–5.16) 0.24 55.19 (27.21–112) 24.60 (12.12–49.93) 0.80 22.02 (11.73–41.34) 10.36 (5.94–18.09) 0.19
6A 8.14 (3.98–16.66) 9.89 (4.83–20.25) 0.66 618 (238–1607) 38.55 (13.44–111) <0.01 209 (72.90–598) 23.02 (7.95–66.66) 0.05
6B 68.12 (16.63–279) 81.54 (22.04–302) 0.82 738 (250–2178) 717 (253–2028) 0.40 522 (184–1479) 643 (266–1553) 0.68
7F 11.87 (5.10–27.64) 10.19 (4.97–20.91) 0.81 1354 (809–2267) 613 (295–1277) 0.21 395 (191–816) 142 (47.69–424) 0.88
9V 94.74 (26.67–337) 73.21 (24.02–223) 0.66 1324 (701–2502) 955 (386–2363) 0.65 1193 (772–1844) 292 (95.85–892) 0.31
14 190 (57.69–624.9) 414 (222–773) 0.24 2544 (1721–3762) 1266 (827–1938) 0.11 1010 (541–1886) 375 (185 762) 0.03
18C 13.69 (4.84–38.74) 7.92 (3.87–16.21) 0.81 1090 (466–2551) 295 (108–806) 0.23 225 (78.75–645) 97.45(34.98272) 0.20
19A 8.84 (5.44–14.38) 17.64 (9.78–31.81) 0.30 239 (127–452) 228 (127–408) 0.55 88.37 (48.72–160) 85.80 (46.80–157) 0.76
19F 10.41 (6.22–17.42) 13.24 (7.12–24.60) 0.31 274 (134–560) 157 (80.43–305) 0.47 57.10 (30.79–106) 30.66 (16.42–57.25) 0.50
23F 7.68 (3.90–15.10) 7.16 (4.03–12.74) 0.81 331 (128–856) 31.65 (11.79–85.00) 0.06 99.02 (37.64–261) 18.32 (8.50–39.52) 0.03

Abbreviations: W, week; PCV 13, 13-valent pneumococcal conjugate vaccine; PPSV23, 23-valent pneumococcal polysaccharide vaccine; number of patients with valid assay results for the specified serotype.

aStudent test or Wilcoxon test b GMTs were calculated using all subjects with available data for the specified blood collection.