Table 2. Summary of InterPro families from downregulated transcripts that were annotated in L. migratoria after PI ingestion.

Putative function	InterPro§	# Seq¥	Description	Fold Change¤
Structural	IPR004000	15	Actin-related protein	0.6–0.7
	IPR002928	6	Myosin	0.7–0.8
	IPR001781	4	Zinc finger, LIM-type	0.6–0.8
	IPR002035	3	von Willebrand factor, type A	0.4–0.7
	IPR013098	2	Immunoglobulin I-set domain	0.7–0.8
	IPR027707	2	Troponin T	0.6–0.7
	IPR001715	1	Calponin homology domain	0.7
	IPR000301	1	Tetraspanin	0.8
	IPR001152	1	Thymosin β-4	0.8
Defense	IPR001304	3	C-type lectin	0.4–0.6
Carbohydrate metabolism	IPR001360	3	β-glucosidase	0.4–0.6
	IPR001312	2	Hexokinase	0.5–0.7
	IPR001701	1	Cellulase	0.7
Lipid metabolism	IPR000566	1	Lipocalin	0.7
	IPR002172	1	Low-density lipoprotein (LDL) receptor class A	0.8
Other metabolism	IPR002198	1	Short-chain dehydrogenase	0.7
	IPR002085	1	Long-chain alcohol dehydrogenase	0.7
	IPR023186	1	Inosine/uridine-nucleoside hydrolase	0.8
	IPR001148	1	Alpha carbonic anhydrase	0.7
	IPR008597	1	Destabilase	0.6
Protein digestion	IPR000994	1	Peptidase M24, aminopeptidase	0.7
	IPR008257	1	Peptidase M19, dipeptidase	0.6
Detox/Stress response	IPR002018	3	Carboxylesterase, type B	0.6–0.7
	IPR002007	1	Haem peroxidase	0.7
	IPR002403	1	Cytochrome P450, E-class, group IV	0.7
	IPR008978	1	Heat shock HSP20-like chaperone	0.6
Other	IPR002048	1	EF-hand domain	0.7
	IPR011011	1	Zinc finger, FYVE/PHD-type	0.7
	IPR001253	1	Translation initiation factor 1A (eIF-1A)	0.6
	IPR020309	1	Uncharacterized protein family, CD034/YQF4	0.7
	IPR004119	1	Protein of unknown function DUF227	0.5
	IPR012464	1	Protein of unknown function DUF1676	0.6

^§InterPro domain ID based on the InterPro database scan⁶⁹.

^¥Number of transcript sequence occurences corresponding to the indicated InterPro ID.

^¤When multiple transcripts are identified the range between the minimal and maximal fold change is presented.