Table 1. Age and dystrophin quantity by DMD mutation.

Mutation group	Individual mutation	Age (years)			Dystrophin (% of control)
		n	Mean ± SD	median (range)	n	Mean ± SD	median (range)
“del 45-x”	del 45–47	10	38.1 ± 13.0	40.1 (10.7~55.9)	5	39 ± 27	28 (10~75)
	del 45–48	14	38.5 ± 17.2	38.0 (9.2~69.6)	12	57 ± 28	49 (16~100)
	del 45–49	2	32.1 ± 17.9	32.1 (19.4~44.7)	1	28 ± NA	28 (28~28)
	del 45–55	2	29.3 ± 31.7	29.3 (6.9~51.6)	2	90 ± 14	90 (80~100)
	“del 45-x” total	28	37.2 ± 16.0	38.3 (6.9~69.6)	20	54 ± 29	49 (10~100)
“del 48”	del 48	10	24.2 ± 19.5	14.5 (6.1~65.8)	7	67 ± 21	58 (40~100)
“del x-51”	del 34–51	1	50.7 ± NA	NA	1	70 ± NA	NA
	del 45–51	5	16.8 ± 6.8	16.2 (8.6~25.7)	4	90 ± 12.5	93 (74~100)
	del 48–51	2	37.8 ± 7.2	37.8 (32.7~42.9)	2	64 ± 24	64 (47~81)
	del 50–51	2	14.3 ± 2.1	14.3 (12.9~15.8)	2	82 ± 18	82 (69~95)
	“del x-51” total	10	23.9 ± 14.1	18.7 (8.6~50.7)	9	80 ± 17	81 (47~100)
“other”	del 3–9	1	13.1 ± NA	NA	1	100 ± NA	NA
	rod domain del*	4	33.7 ± 14.2	29 (22.6~54.2)	4	100 ± 0	100 (100~100)
	del 48–49	3	50.2 ± 13.1	54.7 (35.4~60.3)	3	37 ± 38	30 (3~78)
	duplications	2	39.9 ± 6.9	39.9 (35~44.7)	2	30 ± 35	30 (5~55)
	nonsense	2	28.6 ±  ± 4.8	28.6 (25.2~32)	2	23 ± 8	23 (17~29)
	missense	1	37.6 ± NA	NA	1	13 ± NA	NA
	small deletions	6	35.4 ±  ± 18.1	34.9 (17.4~54.1)	1	39 ± NA	39 (39~39)
	synonym	2	40.7 ± 8	40.7 (35~46.3)	2	23 ± 4	23 (20~26)
	“other” total	21	36.5 ± 14.2	35.0 (16.1~50.3)	16	51 ± 39	34.5 (3~100)
Total		69	33.2 ± 16.5	34.9 (6.1~69.6)	52	59 ± 31	57 (3~100)

SD: standard deviation. del: deletion.

^*Including deletions of exons 10–25, 10–29, del 11–30.