Table 1.
Experimental Design
| Treatment | 0 | 3 | 7 | 14 | 35 | 56 |
|---|---|---|---|---|---|---|
| DEFECT | ||||||
| C57BL/6 | ||||||
| Histology/IHC | 2 | 2 | 2 | |||
| qPCR | 9* | 9* | 9* | |||
| Biomechanics | 7 | 9 | 7 | |||
| MRL/MpJ | ||||||
| Histology/IHC | 2 | 2 | 2 | |||
| qPCR | 9* | 9* | 9* | |||
| Biomechanics | 8 | 10 | 10 | |||
| SHAM | ||||||
| C57BL/6 | ||||||
| Histology/IHC | 2 | 2 | 2 | |||
| Biomechanics | 7 | 9 | 7 | |||
| MRL/MpJ | ||||||
| Histology/IHC | 2 | 2 | 2 | |||
| Biomechanics | 8 | 10 | 10 | |||
| NATIVE | ||||||
| C57BL/6 | ||||||
| Histology/IHC | 2 | |||||
| qPCR | 9* | |||||
| Biomechanics | 14 | |||||
| MRL/MpJ | ||||||
| Histology/IHC | 2 | |||||
| qPCR | 9* | |||||
| Biomechanics | 11 | |||||
The asterix indicates that tissue was collected from 9 animals, but the resulting mRNA was pooled to have a final of 3 independent samples each with mRNA from 3 animals.