Table 2. EBV DNA and EIA antibody responses during the incubation period of infectious mononucleosis.
| EBV assay |
Proportion positive (%) |
Median day positive before onset of symptoms (range) | Median log10 copies per ml or relative antibody units (range)a | |
|---|---|---|---|---|
| Subjects | Samples | |||
| Quantitative DNA | ||||
| Oral cell pellet | 10/11 (91) | 13/31 (42) | 4.0 (1–8) | 4.19 (3.18–6.00) |
| Oral supernatant | 7/11 (64) | 9/31 (29) | 4.0 (2–8) | 2.30 (2.30–5.15) |
| Whole blood | 4/9 (44) | 5/19 (26) | 2.5 (1–8) | 2.60 (2.48–4.48) |
| EIA antibodies | ||||
| VCA IgM | 4/9 (44) | 6/18 (33) | 1.5 (1–36) | 2.50 (1.64–5.25) |
| VCA IgG | 0/9 (0) | 0/18 (0) | — | — |
| gp350 IgG | 5/9 (56) | 7/13 (54) | 22 (4–39) | 38.9 (13.6–85.4) |
Abbreviations: EIA, enzyme immunoassay; VCA, viral capsid antigen.
a
Of positive samples.