Table 1. Top 30 most significant aging-disease associations inferred by GeroNet.
| Disease | FDR | ARD | Disease | FDR | ARD |
|---|---|---|---|---|---|
| Insulin-like growth factors | 1.61E-05 | 1 | Type 2 diabetes | 3.10E-03 | 1 |
| Ovarian cancer | 3.16E-05 | 1 | Thyroid hormone levels | 3.60E-03 | 1 |
| Bladder cancer | 7.47E-05 | 1 | Chronic lymphocytic leukemia | 3.76E-03 | 1 |
| Lung cancer | 1.14E-04 | 1 | Lipoprotein-associated phospholipase A2 activity and mass | 4.98E-03 | 0 |
| Melanoma | 3.40E-04 | 1 | Menopause (age at onset) | 4.99E-03 | 0 |
| Alzheimer’s disease | 5.55E-04 | 1 | Myocardial infarction | 5.11E-03 | 1 |
| Type 2 diabetes and other traits | 5.69E-04 | 1 | Rheumatoid arthritis | 5.75E-03 | 1 |
| Tumor biomarkers | 5.84E-04 | 1 | Basal cell carcinoma | 7.68E-03 | 1 |
| Pancreatic cancer | 6.52E-04 | 1 | Red blood cell count | 8.38E-03 | 0 |
| Thyroid cancer | 1.31E-03 | 0 | Prostate cancer | 9.03E-03 | 1 |
| Acute lymphoblastic leukemia | 1.53E-03 | 0 | Obesity-related traits | 9.29E-03 | 1 |
| Breast cancer | 1.73E-03 | 1 | Adiponectin levels | 1.04E-02 | 1 |
| Myocardial infarction (early onset) | 2.13E-03 | 1 | Cholesterol | 1.12E-02 | 1 |
| Colorectal cancer | 2.50E-03 | 1 | Acne (severe) | 1.12E-02 | 0 |
| Inflammatory bowel disease | 3.10E-03 | 0 | Obesity | 1.27E-02 | 1 |