Table 2.
Correlation between H3S10ph levels of PRM and DRM, ≤4 vs >4 cm
| Total (n = 101) | H3S10 phosphorylation level of PRM ≤4 cm (n = 48) | p value | H3S10 phosphorylation level of PRM >4 cm (n = 53) | p value | ||||
| Low (%), n = 28 | Int. (%), n = 14 | High (%), n = 6 | Low (%), n = 48 | Int. (%), n = 5 | High (%), n = 0 | |||
| WHO classification | ||||||||
| WD | 1 (3.6) | 0 (0.0) | 0 (0.0) | 0.001 ‡ | 1 (2.1) | 0 (0.0) | 0 (0.0) | 0.632‡ |
| MD | 14 (50.0) | 1 (7.1) | 0 (0.0) | 10 (20.8) | 0 (0.0) | 0 (0.0) | ||
| PD | 12 (42.9) | 12 (85.7) | 3 (50.0) | 32 (66.7) | 4 (80.0) | 0 (0.0) | ||
| SRC | 1 (3.6) | 1 (7.1) | 3 (50.0) | 5 (10.4) | 1 (20.0) | 0 (0.0) | ||
| T stage | ||||||||
| T1 | 6 (21.4) | 1 (7.1) | 0 (0.0) | 0.002 † | 7 (14.6) | 0 (0.0) | 0 (0.0) | 0.121† |
| T2 | 10 (35.7) | 2 (14.3) | 0 (0.0) | 12 (25.0) | 0 (0.0) | 0 (0.0) | ||
| T3 | 8 (28.6) | 7 (50.0) | 2 (33.3) | 18 (37.5) | 3 (60.0) | 0 (0.0) | ||
| T4 | 4 (14.3) | 4 (28.6) | 4 (66.7) | 11 (22.9) | 2 (40.0) | 0 (0.0) | ||
| pTNM stage | ||||||||
| I | 10 (35.7) | 2 (14.) | 0 (0.0) | 0.023 † | 10 (20.8) | 0 (0.0) | 0 (0.0) | 0.068† |
| II | 10 (35.7) | 6 (42.9) | 2 (33.3) | 23 (47.9) | 2 (40.0) | 0 (0.0) | ||
| III | 8 (28.6) | 6 (42.9) | 4 (66.7) | 14 (29.2) | 2 (40.0) | 0 (0.0) | ||
| IV | 0 (0.0) | 0 (0.0 | 0 (0.0) | 1 (2.1) | 1 (10.0) | 0 (0.0) | ||
| Recurrence | ||||||||
| Absent | 20 (71.4) | 8 (57.1) | 5 (57.1) | 0.956† | 34 (70.8) | 2 (40.0) | 0 (0.0) | 0.193† |
| Present | 8 (28.6) | 6 (42.9) | 1 (16.7) | 14 (29.2) | 3 (50.0) | 0 (0.0) | ||
| Total (n = 101) | H3S10 phosphorylation level of DRM ≤4 cm (n = 62) | p value | H3S10 phosphorylation level of DRM >4 cm (n = 39) | p value | ||||
| Low (%), n = 24 | Int. (%), n = 34 | High (%), n = 4 | Low (%), n = 33 | Int. (%), n = 6 | High (%), n = 0 | |||
| WHO classification | ||||||||
| WD | 1 (4.2) | 0 (0.0) | 0 (0.0) | 0.0001 ‡ | 1 (3.0) | 0 (0.0) | 0 (0.0) | 0.6‡ |
| MD | 10 (41.7) | 1 (2.9) | 0 (0.0) | 13 (39.4) | 1 (16.7) | 0 (0.0) | ||
| PD | 12 (4.2) | 29 (85.3) | 1 (25.0) | 17 (51.5) | 4 (66.7) | 0 (0.0) | ||
| SRC | 1 (4.2) | 4 (11.8) | 3 (75.0) | 2 (6.1) | 1 (16.7) | 0 (0.0) | ||
| T stage | ||||||||
| T1 | 5 (20.8) | 3 (8.8) | 0 (0.0) | 0.009 | 6 (18.2) | 0 (0.0) | 0 (0.0) | 0.287† |
| T2 | 6 (25.0) | 8 (23.5) | 1 (25.0) | 8 (24.2) | 2 (33.3) | 0 (0.0) | ||
| T3 | 9 (37.5) | 13 (38.2) | 3 (75.0) | 14 (42.4) | 2 (33.3) | 0 (0.0) | ||
| T4 | 4 (16.7) | 10 (29.4) | 0 (0.0) | 5 (15.2) | 2 (33.3) | 0 (0.0) | ||
| pTNM stage | ||||||||
| I | 5 (20.8) | 5 (14.7) | 0 (0.0 | 0.361† | 12 (36.4) | 0 (0.0) | 0 (0.0) | 0.107† |
| II | 9 (37.5) | 17 (50.0) | 1 (25.0) | 13 (39.4) | 3 (50.0) | 0 (0.0) | ||
| III | 10 (41.7) | 11 (32.4) | 3 (75.0) | 7 (21.2) | 3 (50.0) | 0 (0.0) | ||
| IV | 0 (0.0) | 1 (2.9) | 0 (0.0) | 1 (3.0) | 0 (0.0) | 0 (0.0) | ||
| Recurrence | ||||||||
| Absent | 19 (79.2) | 13 (38.2) | 1 (25.0) | 0.031 † | 24 (72.7) | 4 (66.7) | 0 (0.0) | 0.063† |
| Present | 5 (20.8) | 21 (61.8) | 3 (75.0) | 9 (27.3) | 2 (33.3) | 0 (0.0) | ||
All three columns are compared in each category: †chi-square test by two-sided linear-by-linear association; ‡chi-square test by two-sided Fisher’s exact test. Italics indicates values that are statistically significant (<0.05)