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. 2016 Aug 31;16(1):702. doi: 10.1186/s12885-016-2744-9

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 4 — DFX increased caspase 3/7 activity in pancreatic cancer cell lines. BxPC-3, HPAF-II, and Panc 10.05 cells were incubated with the vehicle control (PBS) or DFX at concentrations of 10, 50, or 100 μM for 48 h. Immediately after the incubation, caspase 3/7 activity was measured using a luminescence assay and corrected for cell viability determined using the MTS assay. The corrected caspase 3/7 activities of BxPC-3, HPAF-II, and Panc 10.05 cells incubated with DFX increased in a dose-dependent manner. The data are presented as the mean ± SD (n = 3). *p <0.05, **p <0.01 vs. control