Table 1. Gross tumors in RAG1−/−, Sgo1−/+ and RAG1−/− Sgo1−/+ mice.
RAG1−/− | RAG1−/− Sgo1−/+ | Sgo1−/+ | |
---|---|---|---|
Found dead | 2 (10%) | 6 (37.5%) | 0 (0%) |
Gross lung tumor | 0 (0%) | 6a,b (37.5%) | 3 (9.4%) |
Normal-looking lung | 18 (90%) | 4 (25%) | 29 (90.6%) |
N (total) | 20 | 16 | 32 |
Animal numbers for 12 months end point cohorts.
Significantly different from RAG1−/− mice by Fisher's exact test, P<0.004.
Significantly different from Sgo1−/+ mice by Fisher's exact test, P<0.05.