Figure 2.

Estimation of IC₅₀ and IC₉₀ of Compounds 9, 12, 14, and 18 against promastigotes. Parasites (2 × 10⁶ cells/mL) were incubated with serial four-fold dilutions of test compounds (starting at 25 μM) for 72 h and viability was determined microscopically, as described in methods. Each point or bar corresponds to the mean ± SE of triplicate samples and is representative of one of three independent experiments.