Table 2.
In vitro antibacteriall activity of β-Nitrostyrene.
| Test compounds | Antibacterial activity-MIC in (μg/mL) | |||||||
|---|---|---|---|---|---|---|---|---|
| Sa ATCC 29213 | Se ATCC 14990 | Ec ATCC 25922 | Pa ATCC 27853 | |||||
| MIC | MBC | MIC | MBC | MIC | MBC | MIC | MBC | |
| Cipro | 0.25 | 0.5 | 0.25 | 0.25 | <0.03 | <0.03 | 0.25 | 1.0 |
| 1 | 32 | 32 | 16 | 16 | 32 | 32 | 32 | 64 |
| 2 | >64 | >64 | 32 | 32 | >64 | >64 | >64 | >64 |
| 3 | 4 | 4 | 2 | 2 | >64 | >64 | >64 | >64 |
| 4 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 5 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 6 | >64 | >64 | >64 | >64 | >64 | >64 | >64 | >64 |
| 7 | 8 | 8 | 4 | 4 | 16 | 32 | 16 | 32 |
| 8 | 16 | 32 | 16 | 16 | 64 | >64 | 64 | >64 |
| 9 | 8 | 8 | 4 | 4 | 16 | 32 | 16 | 32 |
| 10 | NT | NT | NT | NT | NT | NT | NT | NT |
| 11 | 8 | 16 | 8 | 8 | 32 | 64 | 64 | >64 |
| 12 | 0.5 | 0.5 | 0.25 | 0.25 | 16 | 16 | 16 | 16 |
| 13 | 64 | 64 | 32 | 32 | >64 | >64 | >64 | >64 |
| 14 | 8 | 8 | 4 | 4 | 64 | >64 | >64 | >64 |
| 15 | 16 | 32 | 16 | 16 | >64 | >64 | >64 | >64 |
| 16 | 64 | >64 | 64 | 64 | 64 | >64 | >64 | >64 |
| 17 | 4 | 4 | 2 | 2 | 16 | 16 | 16 | 32 |
| 18 | 8 | 16* | 8 | 8 | >64 | >64 | >64 | >64 |
| 19 | >64 | >64 | 64 | >64 | >64 | >64 | >64 | >64 |
| 20 | 2 | 4 | 2 | 2 | 16 | 16 | 16 | 32 |
| 21 | 2 | 4 | 2 | 2 | 32 | 64 | 32 | 64 |
| 22 | >64 | >64 | 64 | 64 | >64 | >64 | >64 | >64 |
| 23 | 8 | 16 | 8 | 8 | >64 | >64 | >64 | >64 |
| 24 | NT | NT | NT | NT | NT | NT | NT | NT |
| 25 | NT | NT | NT | NT | NT | NT | NT | NT |
| 26 | 8 | 16 | 8 | 8 | >64 | >64 | >64 | >64 |
| 27 | 32 | 32 | 16 | 16 | >64 | >64 | >64 | >64 |
| 28 | 64 | >64 | 64 | 64 | 64 | >64 | >64 | >64 |
| 29 | 16 | 16 | 8 | 8 | >64 | >64 | >64 | >64 |
| 30 | 16 | 16 | 8 | 8 | 64 | >64 | >64 | >64 |
NT, not tested; Sa, Staphylococcus aureus; Se, Staphylococcus epidermidis; Ec, Escherichia coli; Pa, Pseudomonas aeruginosa; MIC, minimum inhibitory concentration; MBC, minimum bactericidal concentration; Ciprofloxacin served as drug control for bacterial strains. The results are representative of two separate experiments performed in duplicate and similar results were observed each time.