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. 2016 Aug 8;157(9):3604–3620. doi: 10.1210/en.2016-1191

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Figure 7. — PKCδ activation lies upstream of PKA activation in the Gq-mER pathway in PVH CRH neurons. Application of PKA activator forskolin (10 min, 10μM) (A) inhibited the M-current (n = 4) and (B) potentiated mEPSC amplitude (n = 4) and (C) sEPSC amplitude (n = 4). Coperfusion of forskolin (10 min, 10μM) with the PKCδ inhibitor rottlerin (5μM) (D) inhibited the M-current (n = 4) and (E) potentiated mEPSC amplitude (n = 4) and (F) sEPSC amplitude (n = 4). Data were analyzed by a paired Student's t test (*, P < .05; **, P < .01).