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. 2016 Jun 7;157(9):3647–3657. doi: 10.1210/en.2015-1529

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Figure 5. — Sequence conservation of Dnmt3a TREs among mammals. Shown are DNA sequence alignments of the genomic regions containing the TREs at +30.3 kb (number 6) (upper panel) and +49.3 kb (lower panel) from the TSS of the mouse Dnmt3a gene. The boxes indicate the location of the predicated TRE half sites based on the mouse sequences. The TRE at +30.3 kb is a DR+4 in all mammalian species analyzed, whereas the TRE at +49.3 kb is DR+4 in mouse, rat, and Chinese hamster but is DR+5 in other mammals.