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. 2016 Jul 12;157(9):3493–3504. doi: 10.1210/en.2016-1357

Figure 2.

Figure 2.

Loss of 11β-HSD1 does not reduce or delay hepatic lipid accumulation in mice fed the ALIOS diet for 16 weeks. A, Liver to body weight ratios in controls and 11β-HSD1KO. B, Hepatic TAG content in controls and 11β-HSD1KO mice. C, H&E-stained sections cut at 5 μm of controls and 11β-HSD1KO liver demonstrating levels of macro- and microvesicular steatosis. D, Dot plot representing steatosis in livers of control and 11β-HSD1KO mice was assessed using the NAS grading system. Mean ± SEM (A and B), interquartile range (D); n = 13 (control) and n = 11 (11β-HSD1KO). Scale bars, 200 μm.