Table 1.
Patient Characteristics
| All n=200 |
IPF n=134 |
Not IPF n=66 |
p** | |
|---|---|---|---|---|
|
| ||||
| Age (y), Mean (SD) | 64.5 (8.5) | 65.2 (7.2) | 63.1 (10.4) | 0.14 |
|
| ||||
| Male, No. (%) | 104 (52.0) | 73 (54.5) | 31 (47.0) | 0.32 |
|
| ||||
| Race, No. (%) | ||||
| Black | 7 (3.5) | 6 (4.5) | 1 (1.5) | 0.43 |
| White | 184 (92.0) | 120 (89.6) | 64 (97.0) | 0.07 |
| Other | 9 (4.5) | 8 (6.0) | 1 (1.5) | 0.28 |
|
| ||||
| Ever-Smoker, No. (%)* | 106 (53.0) | 67 (51.9) | 39 (59.1) | 0.34 |
|
| ||||
| FVC %-predicted, Mean (SD)* | 69.2 (15.4) | 68.1 (15.2) | 71.4 (15.9) | 0.16 |
|
| ||||
| DLCO %-predicted, Mean (SD)* | 57.5 (17.2) | 55.4 (16.5) | 62.1 (18.0) | 0.02 |
|
| ||||
| Primary HRCT Pattern, No. (%) | ||||
| IPF/UIP | 12 (6.0) | 10 (7.5) | 2 (3.0) | 0.34 |
| NSIP | 135 (67.5) | 94 (70.2) | 41 (62.1) | 0.25 |
| Chronic HP | 18 (9.0) | 10 (7.5) | 8 (12.1) | 0.28 |
| Uncharacterized Fibrosis | 35 (17.5) | 20 (14.9) | 15 (22.7) | 0.17 |
|
| ||||
| Final Clinical Diagnosis, No. (%) | – | – | – | |
| Idiopathic Pulmonary Fibrosis | 134 (67.0) | |||
| Nonspecific Interstitial Pneumonitis | 18 (9.0) | |||
| Hypersensitivity Pneumonia | 33 (16.5) | |||
| Uncharacterized Fibrosis | 10 (5.0) | |||
| Desquamative Interstitial Pneumonia | 2 (1.0) | |||
| Cryptogenic Organizing Pneumonia | 3 (1.5) | |||
*
No. of subjects with missing data: 5 smoking status (patient non-reporting on questionnaire), 3 FVC% (test not performed or reported by referring center), and 23 DLCO% (test not performed or reported by referring center).
**
p-values compare IPF to not IPF patients.
Abbreviations: FVC forced vital capacity, DLCO diffusing capacity of the lung for carbon monoxide, HRCT high resolution computed tomography, IPF idiopathic pulmonary fibrosis, UIP usual interstitial pneumonia, NSIP nonspecific interstitial pneumonia, HP hypersensitivity pneumonia.