Table 3.
Univariable Logistic Regression Model
| Predictor | OR | 95% CI | P |
|---|---|---|---|
|
| |||
| Male Gender | 1.35 | 0.75–2.44 | 0.32 |
|
| |||
| Age, per 5 years | 1.16 | 0.97–1.38 | 0.10 |
|
| |||
| Ever-Smoker | 0.69 | 0.38–1.26 | 0.23 |
|
| |||
| FVC%, Per 10% | 0.87 | 0.72–1.06 | 0.16 |
|
| |||
| Reticular Densities* | 3.29 | 1.77–6.12 | 0.0002 |
|
| |||
| Ground Glass* | 0.50 | 0.31–0.79 | 0.003 |
|
| |||
| Bronchiectasis* | 6.51 | 1.45–29.12 | 0.01 |
|
| |||
| Mosaic Attenuation* | 0.58 | 0.24–1.41 | 0.23 |
|
| |||
| Air Trapping* | 0.56 | 0.17–1.86 | 0.35 |
|
| |||
| Septal Thickening* | 1.07 | 0.38–3.00 | 0.90 |
|
| |||
| Consolidation* | 1.94 | 0.20–18.71 | 0.57 |
|
| |||
| Micronodules* | 0.28 | 0.02–3.78 | 0.34 |
|
| |||
| Axial distribution peripheral/subpleural | 1.82 | 0.87–3.81 | 0.11 |
|
| |||
| Craniocaudal distribution | |||
| Upper lobe | 0.99 | 0.18–5.52 | 0.99 |
| Lower lobe | 0.63 | 0.34–1.17 | 0.15 |
| Diffuse | 1.83 | 0.95–3.51 | 0.07 |
*
The average HRCT whole-lung composites for each HRCT finding, on a scale of 0–4, were the predictor variables of interest; cited OR corresponds to an increase in the whole-lung composite score by 1.
Abbreviations: IPF idiopathic pulmonary fibrosis, FVC% percent predicted forced vital capacity, HRCT high resolution computed tomography.