TABLE 1.
Summary of the dimensionsa of virus-like particles and Gag lattice structures based upon cryo-TEM
| Dimension | RSV | MLV | HTLV-1 | HIV-1 | HIV-2 | HFV |
|---|---|---|---|---|---|---|
| Avg particle diam | 128 (±13.1) | 125 (±33.8) | 116.6 (±27.8) | 141 (±35.1)b | 154.5 (±20.0)b | 82.5 (±29.8) |
| Radius to inner CA subdomain | ∼26 | ∼41 | ∼39 | ∼49 | ∼53 | NDc |
| Radius to outer CA subdomain | ∼39 | ∼51 | ∼44 | ∼55 | ∼60 | ND |
| Distance from lipid bilayer to outer CA subdomain | ∼18 | ∼12 | ∼10 | ∼10 | ∼9 | ND |
| Length of Env protrusions | ND | ND | ND | ND | ND | 16 (±2.1) |
a
All values are averages (± standard deviations) in nanometers.
b
HIV-2-like particles are significantly larger than HIV-1-like particles (t test, P = 0.0002).
c
ND, not determined.