Skip to main content
. Author manuscript; available in PMC: 2017 Sep 1.
Published in final edited form as: Am J Vet Res. 2016 Sep;77(9):1005–1016. doi: 10.2460/ajvr.77.9.1005

Figure 5.

Figure 5

A-C) A dog (Patient 01) with an oral squamous cell carcinoma was given 30 mg/m2 of HA-Pt into the tumor. Three weeks later, the tumor had shrunk into the bone. The dog has received 4 doses (First: 30 mg/m2, second: 30 mg/m2, third: 20 mg/m2, fourth: 10 mg/m2) at 3-week intervals without any toxicity, and the tumor is in a complete remission for 910 days. The dark, lucent areas around the tooth in the CT image of Fig 5C indicated the tumor-free status, which was confirmed by biopsy. D-G) A dog (Patient 10) with oral squamous cell carcinoma was treated with four doses of HA-Pt (First: 10 mg/m2, second: 10 mg/m2, third: 10 mg/m2, fourth: 12.5 mg/m2) at 3-week intervals. The tumor entered a stable partial remission and the inflammation has reversed for 196 days. H&I) A dog (Patient 15) with nasal planum squamous cell carcinoma was given a single injection of 10 mg/m2 HA-Pt. The tumor has receded and no recurrence has been diagnosed 4 months after treatment.