Figure 7. GRB2 rescued miR-329′s inhibition in vitro and in vivo.

Exogenous GRB2 expression in SW1990-miR-329 restored cell colony formation A. and proliferation B. which were inhibited by miR-329. C. Exogenous GRB2 expression in the SW1990-miR-329 cells decreased apoptotic response induced by miR-329. D. Exogenous expression of GRB2 restored tumor growth attenuated by miR-329 expression. Standard deviation of the mean was plotted for bar charts. (* P < 0.05, ** P < 0.01, *** P < 0.001).