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| Cell line | Combination Index (CI) | Drug Reduction Index (DRI) | IC50 (μM) | Synergism/antagonism | ||||
|---|---|---|---|---|---|---|---|---|
| IC50 | IC75 | IC90 | Gefitinib | S3I-201 | Gefitinib | S3I-201 | ||
| 778 | 0.23 | 0.15 | 0.14 | 5.97 | 15.74 | 4.74 | 9.43 | Strong Synergism |
| 449B | 0.34 | 0.61 | 1.10 | 4.15 | 10.56 | 6.98 | 9.04 | Synergism |
| HT1080 | 0.62 | 0.55 | 0.51 | 2.53 | 4.45 | 1.44 | 3.26 | Synergism |
