Figure 7. Ectopic expression of miR-329 promotes apoptosis in A549 and H1299 cells.
A. Quantitative representation of casepase-3 and casepase-7 activity in A549 and H1299 cells transfected with related miRNAs for forty eight hours. B. Shown are representative photomicrographs of cells dual-stained with annexin-FITC/PI. Bar = 10 μm. C. Shown are representative photomicrographs of flow cytometric analysis; Statistical analysis of flow cytometric analysis. D. Western-blot of Bcl2 protein in A549 and H1299 cells after transfection; Statistical analysis of western-blot; qRT-PCR of Bcl2 mRNA in A549 and H1299 cells after transfection; Western-blot of cleaved-caspase-3 protein in A549 and H1299 cells after transfection; Statistical analysis of western-blot. Assays were performed in triplicate Means ± SEM are shown. Statistical analysis was conducted using student t-test.