Table 4. Clinico-pathological features of HCC in relation to β-catenin transcript level.
| Clinico-pathological features | β-catenin^ | P value | |
|---|---|---|---|
| Low | High | ||
| Age | |||
| Young (≤60) | 39 | 15 | 0.879 |
| Elderly (>60) | 17 | 6 | |
| Venous infiltration | |||
| Absent | 29 | 8 | 0.284 |
| Present | 27 | 13 | |
| HBV status | |||
| Negative for HBsAg | 7 | 5 | 0.236 |
| Positive for HBsAg | 48 | 16 | |
| Cellular differentiation (Edmondson-Steiner grade) | |||
| Well-differentiated | 51 | 15 | 0.028 |
| Poorly-differentiated | 5 | 6 | |
| Tumor stage (version UICC7) | |||
| Early stages | 36 | 15 | 0.555 |
| Late stages | 20 | 6 | |
| Tumor size | |||
| Small (≤5cm) | 14 | 4 | 0.583 |
| Large (>5cm) | 42 | 17 | |
| Serum AFP level | |||
| Low (≤400ng/ml) | 37 | 10 | 0.139 |
| High (>400ng/ml) | 19 | 11 | |
| Number of tumor nodules | |||
| Single | 39 | 17 | 0.321 |
| Multiple (≥2) | 17 | 4 | |
^
The cutoff for β-catenin was 12.46, which was the mean value of β-catenin transcript level in HCC.